simule - A Constrained L1 Minimization Approach for Estimating Multiple Sparse Gaussian or Nonparanormal Graphical Models

This is an R implementation of a constrained l1 minimization approach for estimating multiple Sparse Gaussian or Nonparanormal Graphical Models (SIMULE). The SIMULE algorithm can be used to estimate multiple related precision matrices. For instance, it can identify context-specific gene networks from multi-context gene expression datasets. By performing data-driven network inference from high-dimensional and heterogenous data sets, this tool can help users effectively translate aggregated data into knowledge that take the form of graphs among entities. Please run demo(simuleDemo) to learn the basic functions provided by this package. For further details, please read the original paper: Beilun Wang, Ritambhara Singh, Yanjun Qi (2017) <DOI:10.1007/s10994-017-5635-7>.

Last updated 6 years ago

1.30 score 20 scripts 177 downloads

jeek - A Fast and Scalable Joint Estimator for Integrating Additional Knowledge in Learning Multiple Related Sparse Gaussian Graphical Models

Provides a fast and scalable joint estimator for integrating additional knowledge in learning multiple related sparse Gaussian Graphical Models (JEEK). The JEEK algorithm can be used to fast estimate multiple related precision matrices in a large-scale. For instance, it can identify multiple gene networks from multi-context gene expression datasets. By performing data-driven network inference from high-dimensional and heterogeneous data sets, this tool can help users effectively translate aggregated data into knowledge that take the form of graphs among entities. Please run demo(jeek) to learn the basic functions provided by this package. For further details, please read the original paper: Beilun Wang, Arshdeep Sekhon, Yanjun Qi "A Fast and Scalable Joint Estimator for Integrating Additional Knowledge in Learning Multiple Related Sparse Gaussian Graphical Models" (ICML 2018) <arXiv:1806.00548>.

Last updated 6 years ago

1.20 score 16 scripts 127 downloads

diffee - Fast and Scalable Learning of Sparse Changes in High-Dimensional Gaussian Graphical Model Structure

This is an R implementation of Fast and Scalable Learning of Sparse Changes in High-Dimensional Gaussian Graphical Model Structure (DIFFEE). The DIFFEE algorithm can be used to fast estimate the differential network between two related datasets. For instance, it can identify differential gene network from datasets of case and control. By performing data-driven network inference from two high-dimensional data sets, this tool can help users effectively translate two aggregated data blocks into knowledge of the changes among entities between two Gaussian Graphical Model. Please run demo(diffeeDemo) to learn the basic functions provided by this package. For further details, please read the original paper: Beilun Wang, Arshdeep Sekhon, Yanjun Qi (2018) <arXiv:1710.11223>.

Last updated 6 years ago

1.20 score 16 scripts 136 downloads

fasjem - A Fast and Scalable Joint Estimator for Learning Multiple Related Sparse Gaussian Graphical Models

This is an R implementation of "A Fast and Scalable Joint Estimator for Learning Multiple Related Sparse Gaussian Graphical Models" (FASJEM). The FASJEM algorithm can be used to estimate multiple related precision matrices. For instance, it can identify context-specific gene networks from multi-context gene expression datasets. By performing data-driven network inference from high-dimensional and heterogonous data sets, this tool can help users effectively translate aggregated data into knowledge that take the form of graphs among entities. Please run demo(fasjem) to learn the basic functions provided by this package. For more details, please see <http://proceedings.mlr.press/v54/wang17e/wang17e.pdf>.

Last updated 7 years ago

1.20 score 16 scripts 171 downloads